Plotting minutes on datetime axis

I have seen a few discussions of the following issue, so I'm asking about it again.. I am plotting a data point every 5 minutes using the datetime axis and the labels on the axis say 04:49, 09:59, etc. Basically every time being a second short of 05:00, 10:00 etc.  Sometimes it has been 05:01, 10:01 etc. Has there been an authoritative conclusion and possible fix or remedy for such behavior?